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Getting hydroxychloroquine

SchlongConery

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Jan 28, 2013
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This thread seems to have died down along side the alt right hype for HCQ as more results are coming in...

https://jamanetwork.com/journals/jama/fullarticle/2766117

This JAMA article is a fairly strong albeit still observational study.


Conclusions are “ Among patients hospitalized with COVID-19, treatment with hydroxychloroquine, azithromycin, or both was not associated with significantly lower in-hospital mortality.”


Stupid physicians forgot the Zinc...again. I wonder how Dr. PornAddict's clinical trial is coming along?
 

Ben19

Well-known member
Aug 3, 2015
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I appreciate your continuing to inform us about the science behind the epidemic!
I try...

The thing about this whole HCQ thing that bothers me is that it was and still to a certain degree is a VALID option for treatment but it was derailed by politics to the point its hard to do real science on it without bias... But the studies still go on. I think at this point it is VERY Clear HCQ is no wonder drug can I 100% based on my opinion and review of the literature say it is uselless... I still wont say that TBH. I think it may have a role in hyper early administration during the incubation period but it is a small one. That hypothesis is very hard to prove though with studies and it will take time.



I think treatment for this disease is gonna come down to a vaccine or some sort of immunological based treatment. Vaccines are very tricky and that is because they are trying to trick the human immune system which is tricky it self. I often get asked why do vaccines take so long to develope? The reason is because you can faily easily create a vaccine that induces an immune response in the short term the problem is creating a vaccine that creates an immune response that lasts and that is hard not only to do but to test as you have to go through the test of time.
 

SchlongConery

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Jan 28, 2013
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Having mocked PornAddict's obsession with HCQ/Azithromycin/Zinc I do admit that I have read as much as I could find on that trio since the initial reports of its possible efficacy and mode of action. And as a result of that research I have taken the following actions.

1. I changed my daily Calcium/Magnesium supplement to one that includes Zinc. (Just 15 mg of zinc so that probably does nothing except maybe address any zinc deficiency.)

2. I started taking a Turmeric/Curcumin capsule daily (as a zinc ionophore) as I read it might have some effect on the availability of zinc to the virus. Aside from maybe starting to smell like I eat Indian food, I wasn't able to find any adverse effects. It is said to have some ant-inflammatory cardiovascular benefits. I am simply taking it on "no harms" basis.

3. I already have a substantial supply of Quinine on hand. (Quinine is the base drug that HCQ was developed from. I had taken it for a few years for nocturnal leg cramps. At that time, my dose was titrated up along with after-hours ECG testing to look for cardiac rhythm (prolonged QT interval) anomalies and blood testing for a rare but serious blood platelet issue that might arise. It had no adverse effects on me. But I found that stretching and changing the type of extreme physical exercise was more effective. I don't have the need to take it anymore.

4. I also have HCQ and Azithromycin on hand. I travel internationally and also participate in sports and activities that are often remote and far from medical resources. So I have a pretty good home pharmacy. I have taken HCQ prophylactically for travel to malaria. areas. (Another reason I have Quinine on hand) No adverse effects for me from HCQ. I diid. have a bad mental experience with mefloqiune as it gave me really weird dreams.

5 . Despite my best efforts at not becoming infected, IF I do develop identifiable COVID 19 symptoms, I will likely consider self-medicating (at the onset of symptoms) with the Quinine or HCQ with zinc and azithromycin. Max 5 days. I think I'd also consider 81 mg aspirin as an anti-clotting/anti-inflammatory aid as there seems to be some immune over-response/vascular inflammation that seems that it might lead to micro-clots or even large clots.

I figure that since there seems to be no medical treatment except supportive care in hospital if it gets that far, and that I have proven that I do not have adverse responses to any of the drugs, I have more to gain than risk.

Now, if my symptoms develop into respiratory distress/difficulty breathing or low O2 sats (below 95%) ( I have a couple pulse oximeters) I would then quickly go to the hospital for oxygen and put myself in their care.

EDIT: I also already take 4,000 iu Vitamin D3 day. I have read inferences that Vit D deficiency is one reason black people in northern climates are seeming to suffer more frequent and severe COVID 19 infections. (I am not black but have been tested for a few years and found that I have moderate Vit D insufficiency)


Just my crazy isolation musings....
 
Last edited:

danmand

Well-known member
Nov 28, 2003
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Phil does not post about Hydroxychloraquine anymore.
 

mandrill

monkey
Aug 23, 2001
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Phil does not post about Hydroxychloraquine anymore.

Phil has moved on to the shooting in GA. He can only deal with one major issue at a time.

It's unreasonable of you to expect more of him. The internet can be very draining.
 

SchlongConery

License to Shill
Jan 28, 2013
15,333
10,179
113
Stupid physicians forgot the Zinc...again. I wonder how Dr. PornAddict's clinical trial is coming along?

Well I am going to have too eat some crow served by Dr. PornAddict





The following is pre-print/not peer reviewed but seems to be reasonably well thought out and expressed.

Any thoughts on this Ben Casey? ;-)

Hydroxychloroquine and azithromycin plus zinc vs hydroxychloroquine andazithromycin alone: outcomes in hospitalized COVID-19 patients


Just a few highlights for those running short in their Ritalin... (emphasis mine)


"The main finding of this study is that after adjusting for the timing of zinc therapy, wefound that the addition of zinc sulfate to hydroxychloroquine and azithromycin wasfound to associate with a decrease in mortality or transition to hospice among patientswho did not require ICU level of care, but this association was not significant in patientswho were treated in the ICU.


This result may be reflective of the proposed mechanismof action of zinc sulfate in COVID-19. Zinc has been shown to reduce SARS-CoV RNAdependent RNA polymerase activity in vitro [13]. As such, zinc may have a role inpreventing the virus from progressing to severe disease, but once the aberrantproduction of systemic immune mediators is initiated, known as the cytokine storm, theaddition of zinc may no longer be effective [17].

Our findings suggest a potentialtherapeutic synergistic mechanism of zinc sulfate with hydroxychloroquine, if used earlyon in presentation with COVID-19.

However, our findings do not suggest a prophylacticbenefit of zinc sulfate in the absence of a zinc ionophore, despite interest in this therapyfor prevention."
 

mandrill

monkey
Aug 23, 2001
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https://apnews.com/0fbe485717c9a74e...IMmz9HE4v7kYeYa59Ts9VrVPFXYqysWiryeKa4qkTNjtE


WASHINGTON (AP) — President Donald Trump said Monday that he is taking a malaria drug to lessen symptoms should he get the new coronavirus, even though the drug is unproven for fighting COVID-19.

Trump told reporters he has been taking the drug, hydroxychloroquine, and a zinc supplement daily “for about a week and a half now.” Trump spent weeks pushing the drug as a potential cure for COVID-19 against the cautionary advice of many of his administration’s top medical professionals. The drug has the potential to cause significant side effects in some patients and has not been shown to combat the new coronavirus.

Trump said his doctor did not recommend the drug to him, but he requested it from the White House physician.

“I started taking it, because I think it’s good,” Trump said. “I’ve heard a lot of good stories.”

The Food and Drug Administration warned health professionals last month that the drug should not be used outside of hospital or research settings, due to sometimes fatal side effects. Regulators issued the alert after receiving reports of heart-rhythm problems, including deaths, from poison control centers and other health providers.

Trump dismissed reports of side effects, saying, “All I can tell you is, so far I seem to be OK.”

Trump has repeatedly pushed the use of the drug with or without the antibiotic azithromycin, but no large, rigorous studies have found them safe or effective for preventing or treating COVID-19.

Two large observational studies, each involving around 1,400 patients in New York, recently found no benefit from hydroxychloroquine. Two new ones published Thursday in the medical journal BMJ reached the same conclusion.

One, by French researchers, gave 84 hospitalized patients the drug and 97 others the usual care. There were no differences in the odds of death, need for intensive care or developing severe illness.

The other study from China was a stricter test: 150 adults hospitalized with mild or moderate illness were randomly assigned to get hydroxychloroquine or usual care. The drug made no difference in rates of clearing the virus or time to relief of symptoms, and they brought more side effects.

In April, the National Institutes of Health launched a study testing hydroxychloroquine versus a placebo drug in 500 hospitalized COVID-19 patients. Last week, NIH announced another study to see if hydroxychloroquine plus azithromycin can prevent hospitalization or death in people with mild to moderate illness. About 2,000 U.S. adults with confirmed coronavirus infections and symptoms such as fever, cough or shortness of breath will get the drugs or placebo pills.

—-

AP medical writers Marilynn Marchione in Milwaukee and Matthew Perrone in Washington contributed to this report.


And it's silly season once again, folks.
 

Darts

Well-known member
Jan 15, 2017
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"Trump told reporters he has been taking the drug, hydroxychloroquine,"

Trump is famous telling tall tales. Is there any proof?
 

PornAddict

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Go to video time 27:40



Trump have been taking Hyroxychloroquine & Azithromycin ( known also as zpack which is an antibiotics ) with zinc as a preventative medicine quoting “ that frontline hospitals workers as been taking it too as a preventative “ against coronavirus <covid19 > ! Noted he he taken early and noted he mentioned that the bad studies by the VA hospital studies was taken late when the patients already too sick to make any difference! Antivirals work the best when it taken early in symptoms of covid19 or as a preventative medicine!
 

PornAddict

Active member
Aug 30, 2009
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Having mocked PornAddict's obsession with HCQ/Azithromycin/Zinc I do admit that I have read as much as I could find on that trio since the initial reports of its possible efficacy and mode of action. And as a result of that research I have taken the following actions.

1. I changed my daily Calcium/Magnesium supplement to one that includes Zinc. (Just 15 mg of zinc so that probably does nothing except maybe address any zinc deficiency.)

2. I started taking a Turmeric/Curcumin capsule daily (as a zinc ionophore) as I read it might have some effect on the availability of zinc to the virus. Aside from maybe starting to smell like I eat Indian food, I wasn't able to find any adverse effects. It is said to have some ant-inflammatory cardiovascular benefits. I am simply taking it on "no harms" basis.

3. I already have a substantial supply of Quinine on hand. (Quinine is the base drug that HCQ was developed from. I had taken it for a few years for nocturnal leg cramps. At that time, my dose was titrated up along with after-hours ECG testing to look for cardiac rhythm (prolonged QT interval) anomalies and blood testing for a rare but serious blood platelet issue that might arise. It had no adverse effects on me. But I found that stretching and changing the type of extreme physical exercise was more effective. I don't have the need to take it anymore.

4. I also have HCQ and Azithromycin on hand. I travel internationally and also participate in sports and activities that are often remote and far from medical resources. So I have a pretty good home pharmacy. I have taken HCQ prophylactically for travel to malaria. areas. (Another reason I have Quinine on hand) No adverse effects for me from HCQ. I diid. have a bad mental experience with mefloqiune as it gave me really weird dreams.

5 . Despite my best efforts at not becoming infected, IF I do develop identifiable COVID 19 symptoms, I will likely consider self-medicating (at the onset of symptoms) with the Quinine or HCQ with zinc and azithromycin. Max 5 days. I think I'd also consider 81 mg aspirin as an anti-clotting/anti-inflammatory aid as there seems to be some immune over-response/vascular inflammation that seems that it might lead to micro-clots or even large clots.

I figure that since there seems to be no medical treatment except supportive care in hospital if it gets that far, and that I have proven that I do not have adverse responses to any of the drugs, I have more to gain than risk.

Now, if my symptoms develop into respiratory distress/difficulty breathing or low O2 sats (below 95%) ( I have a couple pulse oximeters) I would then quickly go to the hospital for oxygen and put myself in their care.

EDIT: I also already take 4,000 iu Vitamin D3 day. I have read inferences that Vit D deficiency is one reason black people in northern climates are seeming to suffer more frequent and severe COVID 19 infections. (I am not black but have been tested for a few years and found that I have moderate Vit D insufficiency)


Just my crazy isolation musings....
Can I trade you for some HCQ or Quinine and Azithromycin ? I only need one pill of each ! I an even trade Two N95 mask made from USA approved by USA CDC for one pill of HCQ and one pill Azithromycin!
 

Ben19

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Aug 3, 2015
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Go to video time 27:40



Trump have been taking Hyroxychloroquine & Azithromycin ( known also as zpack which is an antibiotics ) with zinc as a preventative medicine quoting “ that frontline hospitals workers as been taking it too as a preventative “ against coronavirus <covid19 > ! Noted he he taken early and noted he mentioned that the bad studies by the VA hospital studies was taken late when the patients already too sick to make any difference! Antivirals work the best when it taken early in symptoms of covid19 or as a preventative medicine!
Taking HCQ as preventative is one thing but now it’s being said to take an antibiotic azithromycin as preventative ?!

I don’t think anyone here realizes how dangerous that is ! Taking antibiotics for no reason can cause the creation resistant organisms. That’s why antibiotics have very strict prescribing criteria. There are whole specialities and efforts into this with antibiotic stewardship. When a person is taking an antibiotic without reason all it does is kill of normal healthy bacteria and it can also create an environment where only resistant bacteria can flourish and if enough people are taking it for long enough the drug will become obsolete as bacteria evolve around it. Thankfully only a handful of idiots are doing it.
 

PornAddict

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Taking HCQ as preventative is one thing but now it’s being said to take an antibiotic azithromycin as preventative ?!

I don’t think anyone here realizes how dangerous that is ! Taking antibiotics for no reason can cause the creation resistant organisms. That’s why antibiotics have very strict prescribing criteria. There are whole specialities and efforts into this with antibiotic stewardship. When a person is taking an antibiotic without reason all it does is kill of normal healthy bacteria and it can also create an environment where only resistant bacteria can flourish and if enough people are taking it for long enough the drug will become obsolete as bacteria evolve around it. Thankfully only a handful of idiots are doing it.
Yeah you right about antibiotics would kill the healthy bacteria in your bio guts. Forgot about that. You need the healthy bacteria in your guts to promote healthy digestion function! Killing all the healthy bacteria in your guts can led to leaky guts disease!
I figure when I am suspected that I come down covid19 the first sign of covid19 and will demand the doctor to prescribe it to me! It my health ! Lost my trust in WHO and Dr Tam ( The Chief Public Health Officer of Canada) and also Health Canada also who told everyone that not to wear a mask during a pandemic ( In the beginning) .
And not declaring a pandemic sooner !And the Fed govt did not shut the border in Feb and allowing people coming into Canada from the Hot zone.

It then better just HCQ and zinc only as a preventative medicine. HCQ is an ionphore allow the zinc get through the cell membrane and that stop the virus from replicating!
Only take antibiotics ( at the same with zinc & HCQ) when you confirm with covid19.
When only as a preventative medicine would take HCQ ( take a low / safe dose providing you don’t have any underline health conditions like heart disease ( Cardiovascular disease) , etc.. and then take zinc at same time.
Unfortunate don’t have a prescription for any of those med ( HCQ & z-pak

Lost my respect on so call expert like medical doctors! Also lost my respect on U.S. CDC and WHO.
It make me realized second opinion and third opinion from medical doctors is now more important! And doing your own research and educating as much on the matter on any disease or your health it more beneficial for yourself!

My mistake Trump been only taking HCQ & Zinc see below post.

PS. I am sure there are good doctors in the health system but unfortunately a few bad apple caused me not trust them blindly anymore!
It will take a long time for the public ( me ) to trust them blindly again!
PPS. Fuck politic and FUCK Trump , Fuck Trudeau, FUCK LEFT OR RIGHT! ( FUCK LIBeral, Fuck Conservatives, Fuck NDP, FUCK REPUBLICan , Fuck democratic, mainstream media!
 

PornAddict

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Trump Admits To Taking Hydroxychloroquine With Zinc As Preventative Measure


President Trump admitted on Monday taking Hydroxychloroquine with zinc as a precaution against coronavirus - telling reporters "I happen to be taking it," and "I'm not going to get hurt by it."

Trump said that while he hasn't been exposed to the virus, he was given permission by the White House doctor to take the controversial treatment, and began taking it approximately 10 days ago - right around the time Mike Pence's press secretary, Katie Miller, tested positive for the virus



"I happen to be taking it," says
@POTUS
of hydroxychloroquine . "I'm not going to get hurt by it."
https://twitter.com/W7VOA/status/12...h/trump-admits-taking-hydroxychloroquine-zinc


Replying to
@W7VOA
"I'd like to take it,"
@POTUS
says he told the
@WhiteHouse
doctor who consented.

Steve Herman
@W7VOA
4h
"A lot of front-line workers" are also taking hydroxychloroquine. "I'm taking the two -- zinc and hydroxy."

https://twitter.com/W7VOA/status/12...h/trump-admits-taking-hydroxychloroquine-zinc

"A lot of good things have come out about the hydroxy. A lot of good things have come out. You’d be surprised at how many people are taking it," said Trump.


While medical experts - including Dr. Anthony Fauci of the White House coronavirus task force have cautioned against taking the drug, Hydroxychloroquine and Zinc has been successfully used by doctors around the world, who claim dramatic improvement in patients with coronavirus.

"Every patient I've prescribed it to has been very, very ill and within 8 to 12 hours, they were basically symptom-free," said Los Angeles doctor Dr. Anthony Cardillo, adding "So clinically I am seeing a resolution."

Cardillo, CEO of Mend Urgent Care, says that the drug must be used in conjunction with Zinc, as the hdroxycholoroquine opens a 'channel' for the mineral to enter cells and prevent the virus from replicating.



Zee Bhaiyah
@Zee_HumHai
·
Apr 6
Replying to
@ANI
Here is the video of
@realDonaldTrump's daily briefing 4/6/2020

https://twitter.com/Zee_HumHai/stat...h/trump-admits-taking-hydroxychloroquine-zinc

That said, the drug has been shown to raise heart risks and rates of death when combined with the antibiotic azithromycin, according to Bloomberg, which notes that it can interfere with the heart's electrical signals in extremely rare cases.
 

Ben19

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Aug 3, 2015
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https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)31180-6/fulltext

Full text above. Published today


If anyone is still on convinced this is a magic drug. New study looking at 96,000 patients says otherwise. Not a RCT but again with all this evidence I wonder how anyone can make the argument that this is some sort of magic pill.

This study is a multi Center registry including over 500 hospitals. It was led by Harvard medical school. They included all patients who got treatment within 48 hours of diagnosis. Given the high numbers (96,000) they were able to control for a lot covariates. They failed to show a treatment effect. Infact they showed that there was higher chance of complications.
 

PornAddict

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https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)31180-6/fulltext


If anyone is still on convinced this is a magic drug. New study looking at 96,000 patients says otherwise. Not a RCT but again with all this evidence I wonder how anyone can make the argument that this is some sort of magic pill.
People are not arguing it a magic pill! Obviously a vaccine is a better alternative!
Until a vaccine is developed this HCQ with Zinc taken early on set of the disease covid19 give you a fighting chance! What the other alternative die ( they is small chance from dying from it) . Think about you & your family members are you willingly gamble your life or health?
And also you willingly risk suffering long term lung damages, suffer kidney damges! Suffer liver damages, suffer long term damges to your health that you may not regain 100 % of your health back!
You know from SARS about 10 year ago not all patients recovered 100 % from SARS still suffering lung damages or long term damage in their health.

People are knowledgeable enough that HCQ with Zinc do provide some positive benefits when taken in the very early onset of symptoms before the patient in incubated stage or in the ICU stage !

It not double blinded random control studies( not peer reviewed) and don't why they the clinical physician not designing the studies as using HCQ with Zinc as a early treatment.

There are benefits when you taken HCQ with Zinc as early as possible! HCQ acts like an ionphore which creates a channel in the cell membrane to allowed Zinc go into the cell which then zinc stop the Covid-19 from replicating! It work like an antivirial agent!

Note antivirial work best when taken early on in the disease not at the late stage an work best as a preventive medicine!
Obviously a vaccine is the best solution ! Meanwhile some people who catch covid19 will die!
To politicized and demonized treatment that provides some benefits will is mind boggling!

PS. Let me as you this question? Answer it as honestly! What happened today you find out you lost the sense of smell and taste and beginng think you may have contracted Covid19. You have been hospitalized yet! Still not in the very early symptoms stage. Would you take HCQ with Zinc treatment?

PPS . FYI For the other posters ,
Prophylactic: A preventive measure. ... A prophylactic is a medication or a treatment designed and used to prevent a disease from occurring. For example, prophylactic antibiotics may be used after a bout of rheumatic fever to prevent the subsequent development of Sydenham's chorea. Please explain why some medical doctors are taking it HCQ with zinc as prophylactic!
 

PornAddict

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HCQ, Moderna, & The Politics Of Pandemic "Medicine"

Authored by Adam Taggart via PeakProsperity.com,
https://www.peakprosperity.com/politicized-medicine/

It sure looks like science is losing out to big money...






Why is hydroxychloroquine (HCQ), one of the most prescribed drugs in history, now suddenly labelled as a lethal threat? And yet barely-tested compounds, like Moderna’s “vaccine”, are quickly and loudly championed?



It’s getting harder and harder to see the inconsistency/hypocrisy as anything but a highly political show in which science is losing out to big money.


Perhaps nothing makes this point more than Moderna and its blockbuster announcement Monday that its “vaccine” generated sufficient antibodies to give recipients immunity to covid-19.

The stock soared as a result…and then the company immediately announced a new funding round.

And now, suddenly experts are saying Moderna hasn’t provided data critical to verifying its claims.

Wait… could Monday’s “news” have been a pump-and-dump con?



And then we find out that the White House’s new “vaccine czar”, Dr Moncef Slaoui, who sat on Moderna’s board up until just a few days ago, is dumping his 156,000 stock options in the company at a sweet price.



Is Moderna being touted because it truly shows more promise than cheap widely-available HCQ? Or because those running the show stand to profit from it? We don’t know for sure, but it sure stinks like it’s the latter.



Don’t forget to get your free download of Peak Prosperity’s book Prosper!. Given its relevance to preparing for any kind of crisis, pandemic or otherwise, Chris and I are now making it available to the world for free during the covid-19 lockdown.

To download your free copy, click here.
https://www.peakprosperity.com/politicized-medicine/
 

Ben19

Well-known member
Aug 3, 2015
770
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The article I posted is peer reviewed published in perhaps one of the most prestigious medical journals in lancet. It is multi Center international trial Conducted by internationally acclaimed experts (chairs in research at Harvard medical school). Your posting opinion pieces and YouTube videos. Why doesn’t this expect of yours who you keep referring to publish his findings and opinions in medical journals ? That’s how things actually get done in medicine and science but he resorts to YouTube videos and directing traffic to his own website. He is just giving opinion with no evidence of his own or a regard for systematic approach to evidence presentation. This guys opinions would not be published in a medical school editorial in a third world country.

Yes this is not a RCT but it sure is very strong evidence it has a N of 96,000 ! You can’t just ignore all the evidence and wait for a RCT to match your opinion. You have to take everything into account and you can’t ignore this massive study.


This whole thing about hcq being preventative may be true to a very small degree. The studies that have supported this hypothesis are very poorly designed and do not account for the very basic fact that patients who are tested prior to symptoms and given HCQ likely represent a significant portion of the asymptomatic group which even without any treatment will not have symptoms so when you include them to show your drug has an effect it is a major co founder.


Also your obsessed with zinc. Are we moving on from hcq to zinc ? To claim that hcq only works with zinc shows a severe lack of understanding of basic physiology.
 
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