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Australian vaccine developer claims 10 years are needed to monitor side-effects

Grist

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Australian vaccine developer claims at least 10 years are needed to monitor side-effects of the new mRNA vaccines.
This is what I've been saying all along.

Protein vaccines are much safer, they've been used for decades now with relatively few side-effects.
Novavax is currently working on a protein-based covid vaccine.
Its pending approval in many Western countries.

A protein vaccine I have no problem taking every 6 to 12 months (or as often as a booster shot is required).
The new Pfizer vaccine I will NOT take every 6 months, you'd have to be crazy to do that.

Background story: https://www.abc.net.au/news/2021-11...per-facing-sack-after-refusing-jabs/100587356

Novavax protein vaccine: https://www.nature.com/articles/d41586-021-03025-0

Watch first 11 minutes of video for better explanation
The MRNA vaccines will be viewed by future generations, as one of the greatest scientific achievements in history.
 

bver_hunter

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Nov 5, 2005
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I have asked him 3 times now what his definition of "long term" is. He has ducked/turtled every time. All of a sudden he is afraid to tell us what he actually means. Please put a number, or range, of years that "long term" means.
Phil states that he has been telling us all along that it will take "at least 10 years to monitor the side effects".
Wonder how many times "all along" is?


Australian vaccine developer claims at least 10 years are needed to monitor side-effects of the new mRNA vaccines.
This is what I've been saying all along.
 

jcpro

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Jan 31, 2014
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I suppose waiting until 2031 to start a vaccine campaign might have some benefits. There would have been a great culling, and herd immunity, and those left alive would definitely have nothing to worry about from the vaccine.

Even better, just like smallpox did, the virus would eventually run out of hosts as all the particularly vulnerable people died off. Given four years it would just, as Trump predicted, fade away. Exactly how it happened with smallpox, several times, after 50-70% of the European population died.

These things do tend to take care of themselves if you wait long enough...and if you don't mind all the dead bodies.
Hmm.... With the survivability north of 99% how in the name of Zeus will Covid run.out of hosts? Have we gone completely bonkers over this?
 

Phil C. McNasty

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So what would be a reasonable amount of time to study mRNA vaccines? 10 years? How about 13?

And the first mRNA vaccine trials on mice was in 1993
Mice =/= human beings
 

Phil C. McNasty

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I understand the two sides, science and anti-science. Forgive me for only respecting one side
And if you knew anything about science you'd know that protein vaccines are proven to be safe because they have been around for a very long time.

Thats why as soon as the Novavax vaccine is approved I'm switching to that one, because it's a protein vaccine and not an mRNA vaccine
 
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Jenesis

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I don't understand why this is so hard to believe. It is not like anyone is saying there IS going to be side effects, just that it will take up to 10 years to see. Makes completely logical sense.

I figured this when I took the vaccine. I fully acknowledged I was taking something found to be safe now but could have effects later.

Why is this an issue?
 
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Phil C. McNasty

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I don't understand why this is so hard to believe. It is not like anyone is saying there IS going to be side effects, just that it will take up to 10 years to see. Makes completely logical sense.

I figured this when I took the vaccine. I fully acknowledged I was taking something found to be safe now but could have effects later.

Why is this an issue?
It shouldnt be an issue, but people with an IQ below 80 seem to wanna make it one
 

Phil C. McNasty

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Novavax vaccine has already been approved by the CDC for air travel in the US, so its looking good right now
 

y2kmark

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I don't understand why this is so hard to believe. It is not like anyone is saying there IS going to be side effects, just that it will take up to 10 years to see. Makes completely logical sense.

I figured this when I took the vaccine. I fully acknowledged I was taking something found to be safe now but could have effects later.

Why is this an issue?
Because there are still chickens out there willing to seize on any pretense to keep some nasty Dr. or nurse (and maybe somebody from a different racial or ethnic group -horrors!) from sticking that sharp needle into their privileged arms...
 

Jenesis

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Because there are still chickens out there willing to seize on any pretense to keep some nasty Dr. or nurse (and maybe somebody from a different racial or ethnic group -horrors!) from sticking that sharp needle into their privileged arms...
So covering it up is the better way to gain their trust?????? LOL

The truth is the truth. You can't hide that and you can't deny that.
 
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Phil C. McNasty

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Here's a good article on mRNA vaccines vs. protein vaccines:



Although slower to develop, protein-based vaccines are well understood with a strong record of safety and effectiveness
There are no protein-based vaccines among the nine candidates in phase 3 clinical trials for Covid-19. The fastest efforts so far rely on inactivated virus, nucleic acids or vector-based strategies.

Yet protein-based vaccines are well established, and will likely work. The most advanced for Covid-19 is from Novavax, based on the entire Sars-CoV-2 spike protein plus an immune system-activating adjuvant. However, perfecting a production system for the spike protein is challenging.

The lead vaccines, which have garnered the lion’s share of attention and funding, were not selected because they’re the best, says Nikolai Petrovsky of Flinders University in Adelaide, Australia. ‘They were just the technologies that were sitting there back in February that governments jumped on,’ he says. Faster is not necessarily better, he warns.

Most protein-based vaccines for Covid-19 employ recombinant versions of the spike protein (or parts of it), which tutors the immune system against wild virus. This works with an adjuvant, a compound that puts frontline immune cells on battle alert, thus mustering a robust immune response to the protein antigen.

In August, Novavax published positive phase 1 data. ‘The Novavax vaccine is looking outstanding,’ says Florian Krammer from the Icahn School of Medicine in New York City, US. ‘They have – so far – the highest neutralising antibody titres I have seen.’ The vaccine also provided sterilising immunity (which stops the virus replicating inside host cells) in non-human primates. Novavax has begun enrolling 2900 volunteers for a phase 2b trial in South Africa.


Protein-based vaccines are going to bulldoze their way to the front, because they are going to be so much better.

Companies also already know how to manufacture recombinant proteins at scale. ‘This is established technology that has been around for decades,’ says Peter Hotez, vaccine scientist at Baylor College of Medicine in Houston, US. ‘They have an excellent record for safety and effectiveness.’ Krammer adds that there is also no risk of immunity to the viral vector reducing the effectiveness of booster doses.
 
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jalimon

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Here's a good article on mRNA vaccines vs. protein vaccines:



Although slower to develop, protein-based vaccines are well understood with a strong record of safety and effectiveness
There are no protein-based vaccines among the nine candidates in phase 3 clinical trials for Covid-19. The fastest efforts so far rely on inactivated virus, nucleic acids or vector-based strategies.

Yet protein-based vaccines are well established, and will likely work. The most advanced for Covid-19 is from Novavax, based on the entire Sars-CoV-2 spike protein plus an immune system-activating adjuvant. However, perfecting a production system for the spike protein is challenging.

The lead vaccines, which have garnered the lion’s share of attention and funding, were not selected because they’re the best, says Nikolai Petrovsky of Flinders University in Adelaide, Australia. ‘They were just the technologies that were sitting there back in February that governments jumped on,’ he says. Faster is not necessarily better, he warns.

Most protein-based vaccines for Covid-19 employ recombinant versions of the spike protein (or parts of it), which tutors the immune system against wild virus. This works with an adjuvant, a compound that puts frontline immune cells on battle alert, thus mustering a robust immune response to the protein antigen.

In August, Novavax published positive phase 1 data. ‘The Novavax vaccine is looking outstanding,’ says Florian Krammer from the Icahn School of Medicine in New York City, US. ‘They have – so far – the highest neutralising antibody titres I have seen.’ The vaccine also provided sterilising immunity (which stops the virus replicating inside host cells) in non-human primates. Novavax has begun enrolling 2900 volunteers for a phase 2b trial in South Africa.

Protein-based vaccines are going to bulldoze their way to the front, because they are going to be so much better.

Companies also already know how to manufacture recombinant proteins at scale. ‘This is established technology that has been around for decades,’ says Peter Hotez, vaccine scientist at Baylor College of Medicine in Houston, US. ‘They have an excellent record for safety and effectiveness.’ Krammer adds that there is also no risk of immunity to the viral vector reducing the effectiveness of booster doses.
Interesting indeed.

But important key point. Novavax is enrolling clinical trial 2. They are late to the game. By the time they finish trial 3 they may end up having the most efficient vaccine but will we need it as much.

Current mrna vaccines have saved millions of lives already.

mrna technology is on a great path for a oncology cancer vaccine. If they succeed it will prevent millions from hard chemotherapy and nasty cancer treatment.

covid pills may be the game changer even before Novovax is out... You get tested positive you take the pill. Bingo! (a bit like chlamydiae or gono ;) )
 
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The Oracle

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covid pills may be the game changer even before Novovax is out... You get tested positive you take the pill. Bingo! (a bit like chlamydiae or gono ;) )
Quite possibly it is already here but has been severely maligned in a attempt for greater profits. 3 CL protease inhibitors could be game changers.

This is a short video explaining why.

 

shack

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Good luck. I've asked 5 times. All of a sudden, Phil does not have such a big mouth. He knows that he's cornered himself.
Phil is so chicken shit to answer my question that he has now put me on ignore.

Nothing more needs to be said. He knows that he's talking out of his ass and I nailed him. LOL

Hey Phil. How many years of testing is "long term"?
 

basketcase

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Mice =/= human beings
Were you incapable of reading where the study talks about HUMAN TRIALS?

But you have convinced me about the 'we don't know' line. I'm moving to a larger place just in case our alien overlords show up and need a place to stay.
 

basketcase

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And if you knew anything about science you'd know that protein vaccines are proven to be safe because they have been around for a very long time.
...
13 years since human trials seems a pretty long time to me. and if you knew anything about science, you'd understand that conclusions rely on evidence.
 
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