Maybe about 10 years ago I was going full on into the work-hard/play-hard philosophy, closing the bar multiple nights a week with work people, and not infrequently hitting the after hours. I don't remember how half those nights ended. At some point along the line I really pissed off a formerly good friend, who refuses to talk to me to this day. I have absolutely no idea why. Something I said or did when I was drunk that I don't remember.
So that was a negative impact.
I'm not an alcoholic and I don't do that so much anymore, I mostly quit after 3-4 drinks these days and I probably only ever even drink once every other week. Every now and then for old time's sake I'll do an all nighter just for fun, but more like a couple of times a year, rather than a couple of times a week, and never on a night when I have to work the next morning, unlike those days.
I think there's a real chance I could have come out of that phase of my life as a raging alcoholic and I'm glad I didn't. But sure, there was at least that impact. Though I have a lot of good memories from those days, so, I don't know... one friend vs about a decade of partying. Not sure I made the wrong choice. Pretty sure I don't want to go back to that lifestyle though.