Do keep in mind that adblock only stops the annoying ads and shit on the computer it is installed on. So if you are asking about videos that you want to upload and share, they will still have the ads when viewed by anyone without adblock.
Still, adblock is the best add-on for browsers ever. No idea why it isn't something EVERYONE has. The very first thing I do on every computer I have bought in the past however many years is install adblock. Cuts down on the visual clutter and annoying bullshit massively.