My biggest individual stock loss was with LOR.TO. Stupid tip from a former boss. He had like six figures in it and was talking about it non stop. I was a broke ass straight out of univeristy student and managed to get 15k worth of it through a margin account. Needless to say, I got ass raped to the tune of about 10k. While not the biggest loss of my life, at the time it hurt like a mutha cuz I was broke. That 10k represented about 80% of my net liquid worth.