South Paw

Baseball stadiums were originally built with home plate to the west (more or less). That way batters could wouldn't have to battle the setting sun in the evening. So left-handed pitchers' pitches came from the "south". I guess the term has been extended to include left-handed athletes and people in general.
 
Two for one

In a two handed grip--Left has to be on top to qualify as Southpaw.


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